Researchers Discover Key To Drought-Resistant Crops

Van Andel Research Institute (VARI) researchers have determined precisely how the plant hormone abscisic acid (ABA) works at the molecular level to help plants respond to environmental stresses such as drought and cold. Their findings, published in the journal Nature, could help engineer crops that thrive in harsh environments around the world and combat global food shortages. The findings could also have implications for stress disorders in humans.

VARI scientists have determined the structure of the receptors that plants use to sense ABA, a hormone that keeps seeds dormant and keeps buds from sprouting until the climate is right. Locating these receptors and understanding how they work is a key finding — one that has eluded researchers for nearly a half-century. This discovery is crucial to understanding how plants respond when they are under stress from extreme temperatures or lack of water.

"The plant community has been waiting for this discovery for many years," says VARI Research Scientist Karsten Melcher, Ph.D., one of the lead authors of the study. "It could have major effects on nutrition and crop yields, especially as fresh water sources become scarcer."

"The work by Dr. Xu and his colleagues, published in one of the most prestigious science journals in the world, will undoubtedly become known as an historic defining moment in our understanding of the mode of action of the important plant hormone abscisic acid," says Grand Valley State University plant development biologist Sheila A. Blackman, Ph.D. "They show how the signaling molecule and its receptor initiate a cascade of events that ultimately affects the expression of genes that are critical for a plant’s survival under harsh conditions. This work has enormous implications for global food supply."

Melcher works in the VARI Laboratory of Structural Biology led by scientific investigator H. Eric Xu, Ph.D. The lab began studying abscisic acid signaling in March this year because a proposed ABA receptor was reported to be a member of G-protein coupled receptors, a group of proteins that the lab studies. More than 50% of all drugs on the market target these proteins, but it has been extremely difficult to determine their atomic structure.

Xu’s laboratory uses a technique known as X-ray crystallography to determine exactly how and why the drug compounds work in molecular detail, which can then help drug developers engineer more potent drugs that have fewer unwanted side effects.

Although it later resulted that the abscisic acid receptors were found to be members of another protein family, Xu’s lab continued their studies on the newly identified ABA receptors. Their findings could help to develop crops that grow in drought, cold, salt water environments, and other harsh conditions, perhaps aiding in stemming or reversing food shortages around the world. Additionally, proteins central to ABA sensing are related to human proteins involved in cellular stress responses and may have implications for stress disorders in humans.

"Proteins with similarities to plant ABA receptors are also found in humans," Xu says. "Further studies in this area could reveal important implications for people with stress disorders."

The lab worked with specialists in plant biology at other institutions to validate the data, including the National Center for Plant Gene Research in Beijing, China, the Department of Botany and Plant Sciences at the University of California at Riverside, the Center for Plant Stress Genomics and Technology at the King Abdullah University of Science and Technology in Thuwal, Saudi Arabia, and the Department of Biochemistry at the Medical College of Wisconsin.

"A finding of this importance helps demonstrate how discoveries at the molecular level in plants can have profound implications for the diseases of humans," says VARI president and research director Dr. Jeffrey Trent. "Remarkably Dr. Xu’s findings (made in only a few short months) will open a decade of research on both plants and man. From a key role in the ripening of fruit through increased understanding of how stress affects a myriad of diseases in man – this finding starts a new chapter in plant and animal biology."

(Source: PRNewswire)

Topics:

Leave a Reply

Crop Inputs Stories

MicronutrientsCharah Add Three Warehouses For SUL4R-PLUS Fertilizer
April 28, 2016
Charah, Inc., a total solutions company providing unparalleled service and innovation for the coal-fired power generation industry, announced today that Read More
Spenser Forgey, Yahama Fortix
FungicidesIndiana Farmer Wins Arysta LifeScience FORTIX Fungicide Sweepstakes
April 28, 2016
Arysta LifeScience North America recently presented Spenser Forgey, a grower from Young America, IN, with a new 2016 Yamaha Grizzly Read More
Corn Field
HerbicidesNew Wilbur‐Ellis Herbicide Targets Volunteer Corn
April 28, 2016
Wilbur‐Ellis Co., a recognized leader in marketing and distribution of crop protection products, as well as precision agriculture technology, has Read More
HerbicidesHELM AGRO Launches New HELM Sulfentrazone 4F Herbicide
April 26, 2016
HELM AGRO US, Inc. has announced the federal Section 3 registration of its new HELM Sulfentrazone 4F herbicide. Classified as a Read More
Trending Articles
Eric SfiligojMissing The Family Ties In Agriculture
April 25, 2016
By its nature, the agriculture market is cyclical. Up and down cycles come and go with a regular pattern. For Read More
HerbicidesHerbicide Resistance In Waterhemp Continues To Grow
April 22, 2016
Twenty-five years ago, waterhemp was virtually unknown to Illinois farmers. Today, the broadleaf weed blankets corn and soybean fields across Read More
Eric SfiligojBiotech Corn Drop More Economics Vs. Consumer Rejection
April 18, 2016
Since their introduction into the agricultural marketplace, biotech crops has steadily grown in acreage in the countries of the world Read More
Crop InputsBayer: 5 Reasons We Disagree With Maryland Neonic Ban
April 12, 2016
We’re disappointed that the Maryland legislature chose not to stand up for sound science and the rights of Maryland’s homeowners Read More
Corn
OpinionChallenging Global Economic Conditions Putting More Heat On U.S. Ag Retailers
April 7, 2016
There it is. That vague, slightly sickening feeling in the pit of my stomach. Things are getting weird out there. Read More
ScoutPro iPad
Precision AgWhat’s Trending In Soil Testing And Scouting
April 6, 2016
Keeping up on soil testing and scouting, especially following unusual weather conditions, can play a role in maximizing yields. Soil Read More
Latest News
BAICOR
CropLife 100BRANDT Acquires Utah Specialty Fertilizer Company
April 28, 2016
BRANDT, a leading agriculture retailer and manufacturer of specialty ag products, has acquired a majority interest in BAICOR, L.C. BAICOR, Read More
Soybean field
Industry NewsVerdesian Life Sciences Adds Vice President Of Business…
April 28, 2016
Verdesian Life Sciences has announced the addition of Marc Treurniet to the plant health and nutrition company’s management team. Treurniet Read More
ManagementBiotech Crops Developments and Millennials
April 28, 2016
Editors Eric Sfiligoj and Paul Schrimpf talk about the latest activities in biotech crops and a major shift in the Read More
Industry NewsNachurs-Alpine, Pathway Biologic Extend Marketing Agree…
April 28, 2016
Nachurs-Alpine Solutions (Marion, OH) and Pathway Biologic (Plant City, FL) announce an extension to their exclusive marketing agreement specific to Read More
MicronutrientsCharah Add Three Warehouses For SUL4R-PLUS Fertilizer
April 28, 2016
Charah, Inc., a total solutions company providing unparalleled service and innovation for the coal-fired power generation industry, announced today that Read More
Spenser Forgey, Yahama Fortix
FungicidesIndiana Farmer Wins Arysta LifeScience FORTIX Fungicide…
April 28, 2016
Arysta LifeScience North America recently presented Spenser Forgey, a grower from Young America, IN, with a new 2016 Yamaha Grizzly Read More
Corn Field
HerbicidesNew Wilbur‐Ellis Herbicide Targets Volunteer Corn
April 28, 2016
Wilbur‐Ellis Co., a recognized leader in marketing and distribution of crop protection products, as well as precision agriculture technology, has Read More
StewardshipNRCS To Help Farmers Measure Conservation Impacts On Wa…
April 27, 2016
The USDA has announced the availability of $2 million to help farmers install edge-of-field stations that monitor water quality as Read More
Planter in Iowa
EquipmentTop 10 Twitter Pics For #Plant16
April 27, 2016
Despite some wet weather in parts of the Midwest, growers and ag retailers are working feverishly to plant this year’s Read More
HerbicidesHELM AGRO Launches New HELM Sulfentrazone 4F Herbicide
April 26, 2016
HELM AGRO US, Inc. has announced the federal Section 3 registration of its new HELM Sulfentrazone 4F herbicide. Classified as a Read More
Valley Irrigation Valley 8000 series on corn
EquipmentValley Irrigation Receives Environmental Stewardship Ho…
April 26, 2016
Valley Irrigation has been recognized as a Groundwater Guardian Green Site by the Groundwater Foundation. The Groundwater Guardian Green Site Read More
Eric SfiligojMissing The Family Ties In Agriculture
April 25, 2016
By its nature, the agriculture market is cyclical. Up and down cycles come and go with a regular pattern. For Read More
HerbicidesHerbicide Resistance In Waterhemp Continues To Grow
April 22, 2016
Twenty-five years ago, waterhemp was virtually unknown to Illinois farmers. Today, the broadleaf weed blankets corn and soybean fields across Read More
ManagementIllinois Leads The Nation In 4R Certified Nutrient Mana…
April 22, 2016
As Illinois agriculture works to educate farmers about minimizing environmental impact and optimizing the use of ag nutrients, Illinois now leads Read More
Social media
Matt Hopkins7 Social Media Trends Shaping Ag Retail In 2016
April 22, 2016
After writing my last column on why social media is a must for ag retailers, I heard from several readers Read More
Industry NewsArysta LifeScience Adds Corey Abels To Midwest Sales Te…
April 22, 2016
Arysta LifeScience North America recently announced the addition of Corey Abels as Territory Sales Manager for the Midwest region. In Read More
Soybean Field
HerbicidesHELM AGRO US Unveils New Sheridan 25 WG Herbicide
April 22, 2016
HELM AGRO US, Inc. has announced the federal Section 3 registration of its new Sheridan 25 WG herbicide for selective Read More
ManagementCentennial’s Jim Fargo Talks Ag Retail
April 21, 2016
Special guest Jim Fargo discusses challenges facing this CropLife 100 retailer. Read More