Researchers Discover Key To Drought-Resistant Crops

Van Andel Research Institute (VARI) researchers have determined precisely how the plant hormone abscisic acid (ABA) works at the molecular level to help plants respond to environmental stresses such as drought and cold. Their findings, published in the journal Nature, could help engineer crops that thrive in harsh environments around the world and combat global food shortages. The findings could also have implications for stress disorders in humans.

VARI scientists have determined the structure of the receptors that plants use to sense ABA, a hormone that keeps seeds dormant and keeps buds from sprouting until the climate is right. Locating these receptors and understanding how they work is a key finding — one that has eluded researchers for nearly a half-century. This discovery is crucial to understanding how plants respond when they are under stress from extreme temperatures or lack of water.

"The plant community has been waiting for this discovery for many years," says VARI Research Scientist Karsten Melcher, Ph.D., one of the lead authors of the study. "It could have major effects on nutrition and crop yields, especially as fresh water sources become scarcer."

"The work by Dr. Xu and his colleagues, published in one of the most prestigious science journals in the world, will undoubtedly become known as an historic defining moment in our understanding of the mode of action of the important plant hormone abscisic acid," says Grand Valley State University plant development biologist Sheila A. Blackman, Ph.D. "They show how the signaling molecule and its receptor initiate a cascade of events that ultimately affects the expression of genes that are critical for a plant’s survival under harsh conditions. This work has enormous implications for global food supply."

Melcher works in the VARI Laboratory of Structural Biology led by scientific investigator H. Eric Xu, Ph.D. The lab began studying abscisic acid signaling in March this year because a proposed ABA receptor was reported to be a member of G-protein coupled receptors, a group of proteins that the lab studies. More than 50% of all drugs on the market target these proteins, but it has been extremely difficult to determine their atomic structure.

Xu’s laboratory uses a technique known as X-ray crystallography to determine exactly how and why the drug compounds work in molecular detail, which can then help drug developers engineer more potent drugs that have fewer unwanted side effects.

Although it later resulted that the abscisic acid receptors were found to be members of another protein family, Xu’s lab continued their studies on the newly identified ABA receptors. Their findings could help to develop crops that grow in drought, cold, salt water environments, and other harsh conditions, perhaps aiding in stemming or reversing food shortages around the world. Additionally, proteins central to ABA sensing are related to human proteins involved in cellular stress responses and may have implications for stress disorders in humans.

"Proteins with similarities to plant ABA receptors are also found in humans," Xu says. "Further studies in this area could reveal important implications for people with stress disorders."

The lab worked with specialists in plant biology at other institutions to validate the data, including the National Center for Plant Gene Research in Beijing, China, the Department of Botany and Plant Sciences at the University of California at Riverside, the Center for Plant Stress Genomics and Technology at the King Abdullah University of Science and Technology in Thuwal, Saudi Arabia, and the Department of Biochemistry at the Medical College of Wisconsin.

"A finding of this importance helps demonstrate how discoveries at the molecular level in plants can have profound implications for the diseases of humans," says VARI president and research director Dr. Jeffrey Trent. "Remarkably Dr. Xu’s findings (made in only a few short months) will open a decade of research on both plants and man. From a key role in the ripening of fruit through increased understanding of how stress affects a myriad of diseases in man – this finding starts a new chapter in plant and animal biology."

(Source: PRNewswire)

Topics:

Leave a Reply

Crop Inputs Stories

Soybean Plant closeup
Crop InputsDow Launching New Soybean Burndown Herbicide
June 30, 2016
With the 2016 growing season nearing the halfway mark, many growers are scouting soybean fields to find unwelcome marestail plants Read More
Valent David Nothmann
Crop InputsValent Names David Nothmann Vice President Of Marketing
June 27, 2016
Valent U.S.A. Corp. has announced the appointment of David Nothmann as vice president of marketing. Nothmann will be responsible for Read More
AdjuvantsPrecision Laboratories Introduces Intact Xtra For Use With Dicamba-Based Herbicides
June 27, 2016
Precision Laboratories announces the launch of Intact Xtra, an adjuvant designed for applicators who want to maximize spray applications and Read More
Crop InputsFields of the Future: WinField Doubles Down with Agri-Education Center Investment (w/Photo Gallery)
June 16, 2016
Land O’Lakes, Inc., joined by Agriculture Secretary Tom Vilsack, today will host Fields of the Future, a live broadcast about Read More
Trending Articles
The Andersons Waterloo
ManagementFirst Indiana Facility Certified Under 4R Nutrient Stewardship Certification Program
June 27, 2016
The 4R Nutrient Stewardship Certification Program has announced that The Andersons, Inc.’s Waterloo, IN, facility has been added to its Read More
Food IT
Industry NewsCalifornia Event Will Mix Ag And Tech Professionals To Explore IT Solutions
June 20, 2016
Silicon Valley is hot on agriculture, and an upcoming event in California will bring together the food and tech industries Read More
Monsanto Luling Plant
Eric SfiligojWhat’s Next For Monsanto?
May 31, 2016
For the folks at Monsanto’s headquarters in St. Louis, MO, it has been an eventful few weeks. Back on May Read More
Soybean Plant closeup
Industry NewsMonsanto Rejects Bayer Bid; Open To More Talks
May 25, 2016
Monsanto Co, the world’s largest seed company, turned down Bayer AG’s $62 billion acquisition bid as “incomplete and financially inadequate” Read More
Eric SfiligojPity The Monsanto Haters
May 23, 2016
An old saying goes thus: “Be careful what you wish for. You just might get it.” Given current events, there Read More
Monsanto Luling Plant
Crop InputsReport: Bayer Eyeing Monsanto For Possible Mega-Merger
May 16, 2016
Bayer AG is exploring a potential bid for U.S. competitor Monsanto Co. in a deal that would create the world’s Read More
Latest News
CHS-Wayland Exterior Dry Fertilizer storage
Retail FacilitiesCHS Expands Michigan Location With New Dome Blending Fa…
July 1, 2016
When CHS wanted to update its Wayland, MI, facility to better serve its customers, it called on Dome Corp. of Read More
Heritage Cooperative
CropLife 100Heritage, Agland Co-op Explore Mutual Merger Interest
June 30, 2016
According to a report in The Ohio Country Journal, Heritage Cooperative and Agland Co-op have entered into negotiations to consider Read More
Soybean Plant closeup
Crop InputsDow Launching New Soybean Burndown Herbicide
June 30, 2016
With the 2016 growing season nearing the halfway mark, many growers are scouting soybean fields to find unwelcome marestail plants Read More
ManagementUpdates on Glyphosate Use in the EU and Bayer/Monsanto
June 29, 2016
Editors Paul Schrimpf and Eric Sfiligoj discuss the latest important developments on these crop protection fronts. Read More
Industry NewsCompass Minerals Names Protassium+ Sales Director
June 28, 2016
Compass Minerals, the producer of Protassium+ sulfate of potash, has named Scott Johnson director of sales for Protassium+ North America. Read More
Eric SfiligojThe British Leave Vote Impact On EU Agriculture
June 27, 2016
Like virtually everyone else in the world this past week, I’ve watched the global reaction to Britain’s vote to exit Read More
Valent David Nothmann
Crop InputsValent Names David Nothmann Vice President Of Marketing
June 27, 2016
Valent U.S.A. Corp. has announced the appointment of David Nothmann as vice president of marketing. Nothmann will be responsible for Read More
The Andersons Waterloo
ManagementFirst Indiana Facility Certified Under 4R Nutrient Stew…
June 27, 2016
The 4R Nutrient Stewardship Certification Program has announced that The Andersons, Inc.’s Waterloo, IN, facility has been added to its Read More
CropLife 100BRANDT Contributes To Mayo Clinic
June 27, 2016
BRANDT, a leading agriculture retailer and manufacturer of specialty agriculture products, has pledged a sizable donation to the Mayo Clinic Read More
ManagementReport: U.S. Farmland Values On Average Continue Gradua…
June 27, 2016
Land price movement has been in the forefront for farmers, landowners, lenders and land brokers for a decade now during Read More
AdjuvantsPrecision Laboratories Introduces Intact Xtra For Use W…
June 27, 2016
Precision Laboratories announces the launch of Intact Xtra, an adjuvant designed for applicators who want to maximize spray applications and Read More
Key Cooperative’s new liquid fertilizer, crop chemical, and seed facility in Grinnell, IA stores 1.5 million gallons of liquid fertilizer and 120,000 gallons of crop chemicals.
Retail FacilitiesKey Cooperative Facility Features The Latest In Murray …
June 27, 2016
When Key Cooperative wanted to improve the overall efficiency at its new state-of-the-art facility in Grinnell, IA, it turned to Read More
Allen Summers Asmark Institute PSM Training
EmployeesAsmark Institute Sponsors 25 ResponsibleAg Auditor Trai…
June 21, 2016
The Asmark Institute has announced plans to provide 25 scholarships through their affiliated State fertilizer and agrichemical associations to help encourage Read More
Kennebec Elevator
CropLife 100Wheat Growers Celebrates Kennebec Elevator Grand Openin…
June 21, 2016
Over 250 patrons and guests were on hand to celebrate Wheat Growers’ Kennebec Elevator grand opening. South Dakota Secretary of Read More
Land O Lakes
Industry NewsLand O’Lakes To Acquire Ceres
June 20, 2016
Land O’ Lakes, Inc. and Ceres, Inc. have announced that they have signed a definitive merger agreement under which Land O’Lakes Read More
Food IT
Industry NewsCalifornia Event Will Mix Ag And Tech Professionals To …
June 20, 2016
Silicon Valley is hot on agriculture, and an upcoming event in California will bring together the food and tech industries Read More
LegislationVilsack Christens WinField Crop Adventure, Talks Monsan…
June 17, 2016
The WinField Crop Adventure grand opening ceremonies at Fair Oaks Farms (near Winemac, IN) welcomed USDA Secretary of Agriculture Tom Read More