Multiple vs. Effective Modes Of Action

Interest in using multiple modes of herbicide action in weed management programs is increasing, according to Aaron Hager, University of Illinois associate professor of weed science.

However, each component of a herbicide premix or tankmix with multiple modes of action is not necessarily effective for every weed or under all application conditions.

For example, giant ragweed, a large-seeded, summer annual, broadleaf weed species, can be difficult to control with a single herbicide. Because of its extended germination and emergence characteristics, farmers may have to use more than one herbicide or multiple herbicide applications.

While herbicide resistance has been found in the Illinois giant ragweed populations, it is not as common or widespread as herbicide resistance in other weed species. Many soil-residual–herbicide premixes containing two or more active ingredients are available to farmers who want to be proactive and use multiple modes of action to reduce the selection for herbicide resistance in giant ragweed.

However, “To effectively reduce the selection intensity for resistance to a particular active ingredient, each component of the premix or tankmix should have similar efficacy against the target weed species,” Hager said. “In addition, each component should demonstrate similar soil persistence.” Few commercial soil-applied herbicide premixes satisfy these criteria when giant ragweed is the target species.

The timing of a herbicide premix or tankmix application can also influence the effectiveness of each component. For example, a farmer may choose to use Harness Xtra (or any other premix of a chloroacetamide and atrazine) to control waterhemp, a small-seeded summer annual broadleaf weed species that has developed resistance and is becoming a serious problem in Illinois fields.

If it is applied before waterhemp seed has germinated, each component of this premix (acetochlor and atrazine) provides effective residual control. However, if the Harness Xtra is not applied until after waterhemp emerges, only the atrazine can effectively control the emerged waterhemp plants.

Similarly, said Hager, “A tankmix of a chloroacetamide herbicide and glyphosate applied after waterhemp emergence does not contain more than one effective mode of action to control emerged waterhemp, nor does it contain more than one effective mode of action for soil-residual control of later-germinating waterhemp.”

Illinois waterhemp populations have evolved resistance to herbicides from at least five herbicide site-of-action families, including inhibitors of acetolactate synthase (ALS), photosystem II (PSII), protoporphyrinogen oxidase (PPO), enolpyruvyl shikimate-3-phosphate (EPSPS) and hydroxyphenyl pyruvate dioxygenase (HPPD). “While not every individual waterhemp plant is resistant to one or more herbicides, most field-level waterhemp populations contain one or more types of herbicide resistance,” said Hager.

Perhaps even more daunting is the occurrence of multiple herbicide resistances within individual plants or fields. Waterhemp plants and populations demonstrating multiple herbicide resistance are becoming increasingly common, can be more difficult to manage, and few herbicide modes of action are effective for their control.

For example, most Illinois waterhemp populations have developed resistance to ALS-inhibiting herbicides, which is often “stacked” with resistance to herbicides from other mode-of-action families. Soil- and foliar-applied herbicide premixes containing various ALS-inhibiting herbicides are numerous. While many of these products do have multiple modes of action, the ALS inhibitor component cannot control ALS-resistant plants.

In a postemergence scenario, applying a premix or tankmix of a diphenylether (PPO inhibitor) and glyphosate (EPSPS inhibitor) provides two effective modes of action against sensitive waterhemp, one effective mode of action against waterhemp resistant to either PPO inhibitors or glyphosate, and no effective modes of action against waterhemp resistant to both PPO inhibitors and glyphosate.

In summary, using herbicides from multiple mode-of-action groups may help reduce the selection intensity for resistance to a particular active ingredient of a herbicide. However, many factors determine the effectiveness of each premix or tankmix ingredient against the weed species of concern.

Leave a Reply

Herbicides Stories
HerbicidesScouting Key To Next Season’s Soybean Herbicide Program
August 12, 2014
When growing soybeans, growers need to think ahead to stay one step ahead of weeds. That means examining weed threats and evaluating which herbicides work best. Read More
Winter Wheat
HerbicidesArysta Touts Burndown Herbicide For Brome Management In Wheat
June 4, 2014
Arysta LifeScience North America recommends PRE-PARE Burndown Herbicide for effective brome management in winter wheat. Read More
HerbicidesFall Herbicide Applications More Effectively Manage Resistant Italian Ryegrass
May 14, 2014
Field studies show that a fall application of certain herbicides before weed emergence, leads to more successful crop planting and weed control in spring. Read More
Waterhemp in soybean stubble
HerbicidesThe Weed Resistance Problem: A Matter Of Billions
April 1, 2014
Not only is the amount of money being spent to control these yield robbers high, but the toll it has taken on the human population is growing lager by the day. Read More
Top 100 Articles
CropLife 100BRANDT Commemorates National Ag Day
March 20, 2015
The Illinois agriculture community gathered at BRANDT global headquarters on March 18 to celebrate National Ag Day behind this year's theme Sustaining Future Generations. Read More
Wheat Growers, North Central Farmers Elevator Pursue Merger
CropLife 100Wheat Growers, North Central Farmers Elevator Pursue Merger
March 3, 2015
Two CropLife 100 retailers — South Dakota Wheat Growers (ranked No. 11) and North Central Farmers Elevator (No. 19) — have entered into a Letter of Intent to unify the two companies into a newly named cooperative. Read More
Growmark Group
CropLife 100GROWMARK In 2015: Back, To The Future
March 2, 2015
The nation’s third largest ag retail organization is simultaneously moving forward while remembering its past. Read More
CropLife 100Pinnacle Expands Sanders Brand In The South
February 27, 2015
Pinnacle has acquired Hopkins Seed and Chemical in Qulin, MO, which expands the company's Sanders brand to nine Southern states. Read More
CropLife 100Pinnacle Launches New Providence Agriculture Location In Indiana
February 27, 2015
Pinnacle Agriculture Holdings — ranked No. 6 on the CropLife 100 — has established a new retail location in New Castle, IN, which will operate as part of Pinnacle's Providence Agriculture brand. Read More
Carl Casale of CHS
CropLife 100Cooperative CHS Returns $518 Million To Owners
February 23, 2015
The 2015 cash return to owners is based on CHS net income of $1.1 billion, the company's second highest on record. Read More
Latest News
FungicidesSyngenta Suing Willowood Over Azoxystrobin Fungicide
March 27, 2015
Syngenta announced today that it has sued agrochemical maker Willowood, LLC., for patent and copyright infringement, as well as unfair Read More
ManagementRetail Week: The Future Of Mycogen Seeds; The 4Rs At Na…
March 27, 2015
Editors Eric Sfiligoj and Matt Hopkins discuss recent trips, including a look at the future of Mycogen Seeds at Dow Read More
Eric SfiligojMonsanto Hears The WHO
March 27, 2015
Another challenge to the safety of glyphosate, and the responses from supporters and opponents, calls to mind a classic Dr. Seuss story. Read More
Industry NewsMonty’s Plant Food Expands Sales Team
March 27, 2015
Monty’s Plant Food Company, a leader in natural soil enhancement and  plant fertility products, has hired Andrew Bullock as a Read More
Crop InputsSyngenta Louisiana Plant Poised For 2015 Production
March 26, 2015
As the 2015 planting season gets underway, growers across the country will need crop protection products to combat pests and Read More
Lake Erie Nutrient Stewardship
LegislationOhio Lawmakers Finalize Phosphorus Restrictions
March 25, 2015
State lawmakers on Wednesday finalized new rules designed to curb toxic algal blooms on Lake Erie, calling the regulations a major step forward in addressing the problem. Read More
Spreaders17 Fertilizer Spreaders For 2015
March 25, 2015
Manufacturers shoot for versatility and accuracy in this year's crop of fertilizer spreaders. Read More
Industry NewsMonty’s Hires Mid-South Product Consultant
March 25, 2015
Monty's Plant Food Co. has hired Matt Woodring as a Product Consultant for portions of Central Kentucky and Tennessee.    Read More
StewardshipMapShots Integrates With DriftWatch
March 23, 2015
Growers and agricultural providers using AgStudio FARM and AgStudio PRO can now view vital information about specialty crops and apiaries through a recent integration with the DriftWatch Specialty Crop Site Registry from FieldWatch, Inc. Read More
Crop InputsWorld Health Organization Report Contradicts Scientific…
March 23, 2015
A new report from the World Health Organization has classified glyphosate with a “2A” rating as a probable carcinogen, a Read More
Eric SfiligojSeed Treatment Stays Necessary
March 20, 2015
Grower-customers looking to scale back spending in 2015 won’t consider seed treatment, say experts. Read More
HerbicidesMARCH MADNESS: Industry Rallies Around Glyphosate Safet…
March 20, 2015
A newly published report from the International Agency for Research on Cancer (IARC) classifies the herbicide glyphosate as a "2A-rated possible carcinogen" and the ag industry responds by circling the wagons. Read More
ManagementRetail Week: Precision survey, a technology acquisition…
March 20, 2015
Editors Paul Schrimpf and Eric Sflilgoj discuss recent travel, the upcoming precision adoption survey, and an unusual sighting at a Read More
CropLife 100BRANDT Commemorates National Ag Day
March 20, 2015
The Illinois agriculture community gathered at BRANDT global headquarters on March 18 to celebrate National Ag Day behind this year's theme Sustaining Future Generations. Read More
Crop InputsBioSafe Launching TerraGrow Soil Inoculant
March 20, 2015
TerraGrow is a blend of beneficial bacterial and fungal spores and nutrients carefully designed to promote healthier soil and crops. Read More
Winter Wheat
AdjuvantsMax Systems Debuts New Adjuvant NanoRevolution 2.0
March 18, 2015
Added to a tank mix of glyphosate at the conservative rate of two to four ounces per acre, NanoRevolution 2.0 has proven effective in killing resistant weed species that had already had up to two applications of the leading glyphosate product. Read More
Photo credit: United Soybean Board/the Soybean Checkoff
Seed/BiotechAgnition Launches Microbial Catalyst Seed Treatment
March 18, 2015
Agnition it has launched Commence for Soybeans, a microbial catalyst seed treatment for soybeans that stimulates microbial activity for healthier soil and a superior growth environment. Read More
4R Certified, Nutrient Stewardship Council,
StewardshipTyler Grain & Fertilizer Now 4R Certified
March 18, 2015
The 4R Nutrient Stewardship Certification Program has announced Tyler Grain & Fertilizer Co. in Smithville, OH, has been added to Read More